logo proMGE v2.0

Explore Mobile Genetic Elements Across Thousands of Prokaryotic Genomes

proMGE is a recombinase-based resource for exploring, annotating and analysing mobile genetic elements (MGEs) across bacterial and archaeal genomes. Browse millions of predicted MGEs, investigate gene functions, antibiotic resistance cargo and nested elements, track horizontal gene transfer and annotate MGEs in your own sequences.

How does proMGE work?

>670K isolate genomes | >180K MAGs | >17 million MGEs

IS element and Transposon (IS_Tn)

Prokaryotic Insertion Sequences (IS) and transposons annotated based on the presence of transposase specific recombinase subfamilies.

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IS_Tn
Integron

Genomic islands containing Integron specific subfamily proteins.
 

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Integron
Phage

MGEs containing Phage recombinase subfamily proteins with phage structural genes in the neighbourhood.

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Phage
Phage_like

MGEs containing only Phage recombinase subfamily proteins without phage structural genes in the neighbourhood.

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Phage like
Conjugative elements (CE)

Plasmids and Integrative Conjugative Elements (ICEs) annotated based on presence of type specific recombinase subfamily proteins and presence of conjugation machinery genes in the neighbourhood.

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Conjugative element
Mobility island (MI)

Genomic islands containing recombinase subfamily proteins common to Phage and Conjugative elements, without the presence of either of phage structural genes or conjugation machinery genes in the neighbourhood.

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Mobility island
Cellular recombinase

Recombinase subfamily protein (Xer-like) associated with host cellular function.
 

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